Home Drugs Review Alocril: A Comprehensive Guide to Ophthalmic Solution for Allergic Conjunctivitis

Alocril: A Comprehensive Guide to Ophthalmic Solution for Allergic Conjunctivitis

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Allergic conjunctivitis, commonly known as eye allergies, affects millions of people worldwide. The condition can be triggered by various allergens such as pollen, dust mites, pet dander, and more. The discomfort and irritation it causes can significantly impact one’s quality of life. Fortunately, there are several treatments available to alleviate the symptoms of allergic conjunctivitis, one of which is Alocril.

Alocril, also known by its generic name Nedocromil, is an ophthalmic solution used to manage the symptoms of allergic conjunctivitis. This article will provide a comprehensive guide to Alocril, exploring its composition, mechanism of action, indications, usage, potential side effects, and more.

Composition and Mechanism of Action

Alocril belongs to a class of drugs called mast cell stabilizers. The active ingredient in Alocril is nedocromil sodium, which helps to relieve the symptoms of allergic conjunctivitis by preventing the release of histamines and other chemical mediators from mast cells. Histamines are substances that contribute to the typical allergy symptoms of itching, redness, and excessive tearing in the eyes.

Nedocromil sodium does not have antihistamine properties, unlike some other allergy eye drops, which primarily block histamine receptors. Instead, it works to inhibit the release of histamines, which effectively helps to prevent or reduce the allergic response in the eyes.


Alocril is primarily indicated for the management of allergic conjunctivitis, a condition characterized by inflammation of the conjunctiva (the thin, clear layer covering the white part of the eye and the inner surface of the eyelids) due to allergic reactions. It can be prescribed for both seasonal and perennial allergic conjunctivitis, making it a versatile treatment option for individuals with allergies triggered by various environmental factors.

Usage and Dosage

Alocril is available as an ophthalmic solution in a sterile, preservative-free form. It comes in a plastic dropper bottle and is applied directly to the eyes. Here’s a general guide on how to use Alocril:

  1. Wash your hands thoroughly before using the eye drops.
  2. Tilt your head backward and look up at the ceiling.
  3. Gently pull down the lower eyelid to create a small pocket.
  4. Hold the dropper bottle with the other hand, and with a steady hand, instill the prescribed number of drops (usually one to two) into the pocket created by pulling down the lower eyelid. Be careful not to touch your eye with the dropper to avoid contamination.
  5. Release the lower eyelid and gently close your eye for a moment to distribute the solution.
  6. If you need to use eye drops in both eyes, repeat the process for the other eye.
  7. Blink a few times to ensure even distribution of the solution.
  8. Wipe away any excess liquid around the eyes.

The typical dosage and frequency of Alocril use will depend on your specific condition and the doctor’s prescription. It is usually administered twice daily, but your healthcare provider will determine the appropriate dosage for you.

Potential Side Effects

While Alocril is generally well-tolerated, like any medication, it can have potential side effects. Common side effects may include:

  1. Temporary burning or stinging sensation in the eyes.
  2. Mild eye irritation.
  3. Watery eyes.
  4. Blurred vision.
  5. Dry eyes.

Serious side effects are rare but may include:

  1. Severe eye irritation.
  2. Eye pain.
  3. Changes in vision.
  4. Signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing.

If you experience severe side effects or any signs of an allergic reaction, seek immediate medical attention.

Precautions and Considerations

Before using Alocril, it’s important to consider the following precautions:

  1. Inform your healthcare provider about any other eye medications you are using, as well as any allergies or medical conditions.
  2. If you wear contact lenses, remove them before applying Alocril and wait at least 10 minutes before reinserting them.
  3. Do not drive or operate heavy machinery if your vision is temporarily impaired after using Alocril.
  4. Alocril should be used as directed by your healthcare provider. Do not increase the dosage or frequency without their approval.
  5. If you miss a dose, apply it as soon as you remember. If it’s close to the time for the next dose, skip the missed dose and continue with your regular schedule.


Alocril, or Nedocromil sodium, is an effective ophthalmic solution for managing allergic conjunctivitis, providing relief from itching, redness, and other discomfort associated with eye allergies. Its mast cell stabilizing mechanism of action distinguishes it from antihistamine-based eye drops, making it a valuable addition to the range of treatment options available for allergy sufferers.

As with any medication, it’s essential to use Alocril as directed by your healthcare provider and be aware of potential side effects. If you experience any unusual or severe symptoms while using Alocril, consult your healthcare professional for guidance. This medication can significantly improve the quality of life for those suffering from allergic conjunctivitis, allowing them to enjoy clear, comfortable vision, even in the midst of allergy season.

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